REACTIVITY OF THE GONADAL SYSTEM IN THE EARLY POST-INTENSIVE CARE PERIOD

Currently, the mechanisms of development of post-resuscitation disease and the development of compensatory processes remain an urgent problem of experimental and clinical resuscitation. The aim of the study was to study the content of sex hormones in plasma and the rate of recovery of neurological status in the early post-intensive care period, after a 5-minute clinical death. 20 male animals were examined who underwent a 5-minute cardiac arrest under ether anesthesia using the method of intrathoracic compression of the vascular bundle of the heart and resuscitation measures were carried out. The content of sex hormones was determined using ELISA in 5 intact animals and 15 in which post-resuscitation disease was simulated. After resuscitation, the condition of the animals is severe; when studying the hormone content after 6 hours, 12 hours and 24 hours, an increase in the blood content of FSH, LH, and testosterone and the activity and irritability of the animals was revealed.

Keywords. Clinical death, post-intensive care disease, sex glands, hormones, follicle stimulating hormone, luteinizing hormone, testosterone.